We do not support restricting or altering network traffic between internal Exchange servers, between internal Exchange servers and internal Lync or Skype for Business servers, or between internal Exchange servers and internal Active Directory domain controllers in any and all types of topologies.
Before we get into that, understand the following ground rules: This topic provides information about the network ports that are used by Exchange Server 2016 and Exchange Server 2019 for communication with email clients, internet mail servers, and other services that are external to your local Exchange organization.
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